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Grand Central Terminal to Columbia University Irving Medical Center by bus and subway

Quick answer: Take the M42 bus from E 42 St/Park Av to W 42 St/8 Av, then take an uptown A train from 42 St-Port Authority Bus Terminal to 168 St. The trip takes about 46 minutes door to door on a weekday (43 to 48 depending on the connection). The M42 bus comes about every 7 minutes during the day. Every line on this trip runs all night.

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Grand Central Terminal to Columbia University Irving Medical Center

Trip timeabout46min
How oftenAbout every 7 minutes (M42)
  • M42
  • A
  1. Walk 1 minto E 42 St/Park Av
  2. M42 M42 busFrom E 42 St/Park Av5 stops, about 11 min
  3. Change at W 42 St/8 AvWalk about 3 min
  4. A A trainFrom 42 St-Port Authority Bus Terminal, uptown4 stops, about 18 min
  5. Get off at 168 St
  6. Columbia University Irving Medical CenterWalk about 9 min

Weekdays, fall 2026 MTA schedule · First and last trips

Step by step

  1. Walk about 1 minute from Grand Central Terminal to E 42 St/Park Av.
  2. Take the M42 bus from E 42 St/Park Av to W 42 St/8 Av. It's 5 stops, about 11 minutes.
  3. At W 42 St/8 Av, walk about 3 minutes to 42 St-Port Authority Bus Terminal for the A train.
  4. Take an uptown A train from 42 St-Port Authority Bus Terminal to 168 St. It's 4 stops, about 18 minutes.
  5. From 168 St, walk about 9 minutes to Columbia University Irving Medical Center.

Times and frequency

From the MTA's fall 2026 schedule. Typical trip is the door to door time in the middle of the day.

DayFirst tripLast tripTypical tripA train in the daytime
WeekdaysRuns all night46 minAbout every 7 minutes
SaturdayRuns all night47 minAbout every 10 minutes
SundayRuns all night43 minAbout every 10 minutes

Late at night

This trip works around the clock. Between about 1 and 5 am the trip takes about 54 minutes, and the A train comes about every 20 minutes.

Tips for this trip

Step-free access

For the subway part of this trip: Times Sq-42 St/Port Authority Bus Terminal (A platform) is on the MTA's list of accessible stations; 168 St-Washington Hts (A platform) is on the MTA's list of accessible stations. Elevators can be out of service, so check elevator status on mta.info before you go.

What it costs

Fares as of November 2026. Check the official fares page before you ride.

Grand Central Terminal to Columbia University Irving Medical Center: common questions

How do I get from Grand Central Terminal to Columbia University Irving Medical Center by public transit?

Take the M42 bus from E 42 St/Park Av to W 42 St/8 Av, then take an uptown A train from 42 St-Port Authority Bus Terminal to 168 St.

How long does it take?

About 46 minutes door to door on a weekday, 43 to 48 depending on the connection. On weekends it's about 47 minutes.

Do I have to change along the way?

Yes, once: at W 42 St/8 Av.

Does it run all night?

This trip works around the clock. Between about 1 and 5 am the trip takes about 54 minutes, and the A train comes about every 20 minutes.

How much does it cost?

Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.

Sources

Cobblehop is independent. It is not affiliated with the MTA or any transit agency. Schedules on this page come from the MTA's public GTFS data; check these pages for the latest service:

Transit data: Metropolitan Transportation Authority (MTA). Cobblehop is not affiliated with or endorsed by the MTA.

Published November 7, 2026. Times were computed from the MTA fall 2026 schedules for 2026-11-18 (weekday), 2026-11-21 and 2026-11-22. Planned work and holidays change service, so check Cobblehop for live times before you go.

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