Penn Station to Mount Sinai Hospital by subway and bus
Quick answer: Take an uptown 2 or 3 train from 34 St-Penn Station to 110 St-Malcolm X Plaza, then take the M2 bus from Central Park North/Malcolm X Blvd to 5 Av/E 102 St. The trip takes about 37 minutes door to door on a weekday (35 to 39 depending on the connection). The 2 or 3 train comes about every 4 minutes during the day. Every line on this trip runs all night.
Penn Station to Mount Sinai Hospital
- 2 / 3
- M2
- 2 / 3 2 or 3 trainFrom 34 St-Penn Station, uptown4 stops, about 14 min
- Change at 110 St-Malcolm X PlazaWalk about 7 min
- M2 M2 busFrom Central Park North/Malcolm X Blvd3 stops, about 8 min
- Get off at 5 Av/E 102 St
- Mount Sinai HospitalWalk about 2 min
Weekdays, fall 2026 MTA schedule · First and last trips
Step by step
- Take an uptown 2 or 3 train from 34 St-Penn Station to 110 St-Malcolm X Plaza. It's 4 stops, about 14 minutes.
- At 110 St-Malcolm X Plaza, walk about 7 minutes to Central Park North/Malcolm X Blvd for the M2 bus.
- Take the M2 bus from Central Park North/Malcolm X Blvd to 5 Av/E 102 St. It's 3 stops, about 8 minutes.
- From 5 Av/E 102 St, walk about 2 minutes to Mount Sinai Hospital.
Other ways to go
- Take an uptown 2 or 3 train from 34 St-Penn Station to 96 St, then take the M106 bus from W 96 St/Broadway to Madison Av/E 101 St: about 38 minutes.
- Take an uptown 2 or 3 train from 34 St-Penn Station to 110 St-Malcolm X Plaza, then take the M4 bus from Central Park North/Malcolm X Blvd to 5 Av/E 102 St: about 39 minutes.
Which one is faster depends on when you leave. Cobblehop compares them with live times.
Times and frequency
From the MTA's fall 2026 schedule. Typical trip is the door to door time in the middle of the day.
| Day | First trip | Last trip | Typical trip | 2 or 3 train in the daytime |
|---|---|---|---|---|
| Weekdays | Runs all night | 37 min | About every 4 minutes | |
| Saturday | Runs all night | 33 min | About every 4 minutes | |
| Sunday | Runs all night | 35 min | About every 4 minutes | |
Late at night
This trip works around the clock. Between about 1 and 5 am the trip takes about 37 minutes, and the 2 or 3 train comes about every 10 minutes.
Tips for this trip
- Take the first train that comes. The 2 and 3 trains all stop at both 34 St-Penn Station and 110 St-Malcolm X Plaza.
- Newark Penn Station is a different station, in Newark, New Jersey. (source, checked 2026-11-04)
- Moynihan Train Hall, across the street, serves LIRR and Amtrak riders too. (source, checked 2026-11-04)
Step-free access
For the subway part of this trip: 34 St-Penn Station (2 platform) is on the MTA's list of accessible stations; 110 St-Malcolm X Plaza (2 platform) is not on the MTA's list of accessible stations. Elevators can be out of service, so check elevator status on mta.info before you go.
What it costs
- Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Fares as of November 2026. Check the official fares page before you ride.
Penn Station to Mount Sinai Hospital: common questions
How do I get from Penn Station to Mount Sinai Hospital by public transit?
Take an uptown 2 or 3 train from 34 St-Penn Station to 110 St-Malcolm X Plaza, then take the M2 bus from Central Park North/Malcolm X Blvd to 5 Av/E 102 St.
How long does it take?
About 37 minutes door to door on a weekday, 35 to 39 depending on the connection. On weekends it's about 33 minutes.
Do I have to change along the way?
Yes, once: at 110 St-Malcolm X Plaza.
Does it run all night?
This trip works around the clock. Between about 1 and 5 am the trip takes about 37 minutes, and the 2 or 3 train comes about every 10 minutes.
How much does it cost?
Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Related routes
- Penn Station to Rockefeller Center
- Penn Station to 9/11 Memorial & Museum
- Penn Station to Statue of Liberty ferry at Battery Park
- JFK Airport to Mount Sinai Hospital
- LaGuardia Airport to Mount Sinai Hospital
- Grand Central Terminal to Mount Sinai Hospital
- All New York routes
Sources
Cobblehop is independent. It is not affiliated with the MTA or any transit agency. Schedules on this page come from the MTA's public GTFS data; check these pages for the latest service:
- MTA: developer data (the GTFS schedules used on this page)
- MTA: subway and bus fares
- MTA subway stations, with accessibility (data.ny.gov)
- Penn Station: visitor information
- Penn Station: visitor information
Transit data: Metropolitan Transportation Authority (MTA). Cobblehop is not affiliated with or endorsed by the MTA.
Published November 7, 2026. Times were computed from the MTA fall 2026 schedules for 2026-11-18 (weekday), 2026-11-21 and 2026-11-22. Planned work and holidays change service, so check Cobblehop for live times before you go.
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