Grand Central Terminal to NewYork-Presbyterian / Weill Cornell Medical Center by subway and bus
Quick answer: Take an uptown 6 train from Grand Central-42 St to 68 St-Hunter College, then take the M66 bus from E 68 St/Lexington Av to E 68 St/York Av. The trip takes about 25 minutes door to door on a weekday (22 to 27 depending on the connection). The 6 train comes about every 4 minutes during the day. The M66 bus runs only a few times from E 68 St/Lexington Av to E 68 St/York Av between about 1 and 5 am; then the trip uses another line.
Grand Central Terminal to NewYork-Presbyterian / Weill Cornell Medical Center
- 6
- M66
- Walk 4 minto Grand Central-42 St
- 6 6 trainFrom Grand Central-42 St, uptown3 stops, about 5 min
- Change at 68 St-Hunter CollegeWalk about 4 min
- M66 M66 busFrom E 68 St/Lexington Av4 stops, about 6 min
- Get off at E 68 St/York Av
- NewYork-Presbyterian / Weill Cornell Medical CenterWalk about 3 min
Weekdays, fall 2026 MTA schedule · First and last trips
Step by step
- Walk about 4 minutes from Grand Central Terminal to Grand Central-42 St.
- Take an uptown 6 train from Grand Central-42 St to 68 St-Hunter College. It's 3 stops, about 5 minutes.
- At 68 St-Hunter College, walk about 4 minutes to E 68 St/Lexington Av for the M66 bus.
- Take the M66 bus from E 68 St/Lexington Av to E 68 St/York Av. It's 4 stops, about 6 minutes.
- From E 68 St/York Av, walk about 3 minutes to NewYork-Presbyterian / Weill Cornell Medical Center.
Other ways to go
- Take the M2 bus from Madison Av/E 43 St to Madison Av/E 67 St, then take the M66 bus from Madison Av/E 67 St to E 68 St/York Av: about 30 minutes.
- Take the M42 bus from E 42 St/Park Av to E 41 St/1 Av, then take the M15 Select Bus Service bus from 1 Av/E 43 St to 1 Av/E 67 St: about 26 minutes.
Which one is faster depends on when you leave. Cobblehop compares them with live times.
Times and frequency
From the MTA's fall 2026 schedule. Typical trip is the door to door time in the middle of the day.
| Day | First trip | Last trip | Typical trip | M66 bus in the daytime |
|---|---|---|---|---|
| Weekdays | Around the clock (another line late at night) | 25 min | About every 6 minutes | |
| Saturday | Around the clock (another line late at night) | 23 min | About every 10 minutes | |
| Sunday | Around the clock (another line late at night) | 29 min | About every 12 minutes | |
Late at night
This trip works around the clock. Between about 1 and 5 am the trip takes about 23 minutes. The M66 bus runs only a few times from E 68 St/Lexington Av to E 68 St/York Av between about 1 and 5 am, so at that hour the trip uses another line.
Tips for this trip
- Know your stop. Get ready after E 68 St/1 Av. The next stop is E 68 St/York Av. Start a live trip in Cobblehop and it alerts you before your stop.
- LIRR trains stop at Grand Central Madison, on the west side of Grand Central Terminal, under Vanderbilt Avenue. (source, checked 2026-11-04)
Step-free access
For the subway part of this trip: Grand Central-42 St (6 platform) is on the MTA's list of accessible stations; 68 St-Hunter College (6 platform) is on the MTA's list of accessible stations. Elevators can be out of service, so check elevator status on mta.info before you go.
What it costs
- Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Fares as of November 2026. Check the official fares page before you ride.
Grand Central Terminal to NewYork-Presbyterian / Weill Cornell Medical Center: common questions
How do I get from Grand Central Terminal to NewYork-Presbyterian / Weill Cornell Medical Center by public transit?
Take an uptown 6 train from Grand Central-42 St to 68 St-Hunter College, then take the M66 bus from E 68 St/Lexington Av to E 68 St/York Av.
How long does it take?
About 25 minutes door to door on a weekday, 22 to 27 depending on the connection. On weekends it's about 23 minutes.
Do I have to change along the way?
Yes, once: at 68 St-Hunter College.
Does it run all night?
This trip works around the clock. Between about 1 and 5 am the trip takes about 23 minutes. The M66 bus runs only a few times from E 68 St/Lexington Av to E 68 St/York Av between about 1 and 5 am, so at that hour the trip uses another line.
How much does it cost?
Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Related routes
- Grand Central Terminal to 9/11 Memorial & Museum
- Grand Central Terminal to Statue of Liberty ferry at Battery Park
- Grand Central Terminal to Central Park
- Penn Station to NewYork-Presbyterian / Weill Cornell Medical Center
- Port Authority Bus Terminal to NewYork-Presbyterian / Weill Cornell Medical Center
- All New York routes
Sources
Cobblehop is independent. It is not affiliated with the MTA or any transit agency. Schedules on this page come from the MTA's public GTFS data; check these pages for the latest service:
- MTA: developer data (the GTFS schedules used on this page)
- MTA: subway and bus fares
- MTA subway stations, with accessibility (data.ny.gov)
- Grand Central Terminal: visitor information
Transit data: Metropolitan Transportation Authority (MTA). Cobblehop is not affiliated with or endorsed by the MTA.
Published November 7, 2026. Times were computed from the MTA fall 2026 schedules for 2026-11-18 (weekday), 2026-11-21 and 2026-11-22. Planned work and holidays change service, so check Cobblehop for live times before you go.
Leaving now? Cobblehop gives you one clear plan with live times and alerts you before your stop.
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