Port Authority Bus Terminal to NewYork-Presbyterian / Weill Cornell Medical Center by bus
Quick answer: Take the M104 bus from W 41 St/8 Av to Broadway/W 63 St, then take the M66 bus from W 65 St/Columbus Av to E 68 St/York Av. The trip takes about 41 minutes door to door on a weekday (33 to 44 depending on the connection). The M104 bus comes about every 12 minutes during the day. The M66 bus runs only a few times from W 65 St/Columbus Av to E 68 St/York Av between about 1 and 5 am; then the trip uses another line.
Port Authority Bus Terminal to NewYork-Presbyterian / Weill Cornell Medical Center
- M104
- M66
- Walk 1 minto W 41 St/8 Av
- M104 M104 busFrom W 41 St/8 Av7 stops, about 11 min
- Change at Broadway/W 63 StWalk about 2 min
- M66 M66 busFrom W 65 St/Columbus Av9 stops, about 22 min
- Get off at E 68 St/York Av
- NewYork-Presbyterian / Weill Cornell Medical CenterWalk about 3 min
Weekdays, fall 2026 MTA schedule · First and last trips
Step by step
- Walk about 1 minute from Port Authority Bus Terminal to W 41 St/8 Av.
- Take the M104 bus from W 41 St/8 Av to Broadway/W 63 St. It's 7 stops, about 11 minutes.
- At Broadway/W 63 St, walk about 2 minutes to W 65 St/Columbus Av for the M66 bus.
- Take the M66 bus from W 65 St/Columbus Av to E 68 St/York Av. It's 9 stops, about 22 minutes.
- From E 68 St/York Av, walk about 3 minutes to NewYork-Presbyterian / Weill Cornell Medical Center.
Other ways to go
- Take the M104 bus from W 41 St/8 Av to 8 Av/W 56 St, then take the M31 bus from W 57 St/8 Av to York Av/E 69 St: about 42 minutes.
- Take the M20 bus from 8 Av/W 41 St to Central Park West/W 63 St, then take the M66 bus from W 65 St/Central Park West to E 68 St/York Av: about 42 minutes.
Which one is faster depends on when you leave. Cobblehop compares them with live times.
Times and frequency
From the MTA's fall 2026 schedule. Typical trip is the door to door time in the middle of the day.
| Day | First trip | Last trip | Typical trip | M66 bus in the daytime |
|---|---|---|---|---|
| Weekdays | Around the clock (another line late at night) | 41 min | About every 7 minutes | |
| Saturday | Around the clock (another line late at night) | 39 min | About every 10 minutes | |
| Sunday | Around the clock (another line late at night) | 40 min | About every 12 minutes | |
Late at night
This trip works around the clock. Between about 1 and 5 am the trip takes about 29 minutes. The M66 bus runs only a few times from W 65 St/Columbus Av to E 68 St/York Av between about 1 and 5 am, so at that hour the trip uses another line.
Tips for this trip
- Know your stop. Get ready after E 68 St/1 Av. The next stop is E 68 St/York Av. Start a live trip in Cobblehop and it alerts you before your stop.
What it costs
- Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Fares as of November 2026. Check the official fares page before you ride.
Port Authority Bus Terminal to NewYork-Presbyterian / Weill Cornell Medical Center: common questions
How do I get from Port Authority Bus Terminal to NewYork-Presbyterian / Weill Cornell Medical Center by public transit?
Take the M104 bus from W 41 St/8 Av to Broadway/W 63 St, then take the M66 bus from W 65 St/Columbus Av to E 68 St/York Av.
How long does it take?
About 41 minutes door to door on a weekday, 33 to 44 depending on the connection. On weekends it's about 39 minutes.
Do I have to change along the way?
Yes, once: at Broadway/W 63 St.
Does it run all night?
This trip works around the clock. Between about 1 and 5 am the trip takes about 29 minutes. The M66 bus runs only a few times from W 65 St/Columbus Av to E 68 St/York Av between about 1 and 5 am, so at that hour the trip uses another line.
How much does it cost?
Subway and local bus: $3 per ride with OMNY (tap a contactless card or phone) or a MetroCard. One transfer within 2 hours to the subway or a local bus is included.
Related routes
- Port Authority Bus Terminal to Empire State Building
- Port Authority Bus Terminal to 9/11 Memorial & Museum
- Port Authority Bus Terminal to Statue of Liberty ferry at Battery Park
- Penn Station to NewYork-Presbyterian / Weill Cornell Medical Center
- Grand Central Terminal to NewYork-Presbyterian / Weill Cornell Medical Center
- All New York routes
Sources
Cobblehop is independent. It is not affiliated with the MTA or any transit agency. Schedules on this page come from the MTA's public GTFS data; check these pages for the latest service:
Transit data: Metropolitan Transportation Authority (MTA). Cobblehop is not affiliated with or endorsed by the MTA.
Published November 7, 2026. Times were computed from the MTA fall 2026 schedules for 2026-11-18 (weekday), 2026-11-21 and 2026-11-22. Planned work and holidays change service, so check Cobblehop for live times before you go.
Leaving now? Cobblehop gives you one clear plan with live times and alerts you before your stop.
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